An ex-vivo study on human skin samples showed that topical diclofenac not only penetrates the skin but also forms a reservoir of the drug in the epidermis. Confirmation that the drug reaches the site ...
The experimental study investigated the bioadhesive properties of cough syrups containing partial fractions of plant extracts with or without added honey. The study authors established that addition o ...
Results of two single-dose studies (randomised, single centre, crossover, open-label)
Analgesics containing readily soluble ibuprofen (e.g. as the lysinate) were developed with the aim of ensuring a more rapid relief of pain than ibuprofen acid through faster absorption in the gastroin ...
Results of a clinical study (randomised, placebo-controlled, double-blind)
Does combining ibuprofen with caffeine have advantages over ibuprofen alone in the treatment of acute pain? A randomised, placebo-controlled, double-blind study compared efficacy, safety and tolerabil ...
Abdominal pain is common and impairs quality of life. Many specialist societies across the world have formulated guidelines on the treatment of irritable bowel syndrome and all of them mention antispa ...
Relief that is rapid and effective is wanted when treating pain. A double-blind, placebo-controlled study investigated the efficacy, safety and tolerability of ibuprofen lysinate, ibuprofen acid and p ...
The meta-analysis demonstrated that peppermint oil is an effective and safe medicinal agent for treating the symptoms of irritable bowel syndrome. In seven clinical studies, peppermint oil was clearly ...
No relevant effects on the sleep quality of subjects were found in two studies in which ibuprofen combined with 100 mg caffeine was taken three times daily. Of a total of 538 patients, medication-indu ...
A review by the Cochrane Collaboration compared the analgesic effects of a common analgesic with a combination of the analgesic and caffeine. The addition of caffeine significantly increased the propo ...
Various causes, including stress and increased media consumption, lead to a reduction or even total absence of the release of endogenous melatonin, followed by problems falling asleep. According to th ...
