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Marshmallow root extract and honey: cough relief through mucoprotection


The experimental study investigated the bioadhesive properties of cough syrups containing partial fractions of plant extracts with or without added honey. The study authors established that addition o ...

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Автор: Tobias Mück, PhDEFSM: 2021;1:210005DOI: 10.52778/efsm.21.0005Дата: 16.08.2021

Pharmacokinetics of ibuprofen: comparison of the fixed combination of ibuprofen plus caffeine with …

Results of two single-dose studies (randomised, single centre, crossover, open-label)


Analgesics containing readily soluble ibuprofen (e.g. as the lysinate) were developed with the aim of ensuring a more rapid relief of pain than ibuprofen acid through faster absorption in the gastroin ...

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Автор: Thomas Weiser, PhDEFSM: 2021;1:210007DOI: 10.52778/efsm.21.0007Дата: 16.08.2021

Efficacy, safety and tolerability of the fixed combination of ibuprofen (400 mg) and caffeine (100 …

Results of a clinical study (randomised, placebo-controlled, double-blind)


Does combining ibuprofen with caffeine have advantages over ibuprofen alone in the treatment of acute pain? A randomised, placebo-controlled, double-blind study compared efficacy, safety and tolerabil ...

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Автор: Thomas Weiser, PhDEFSM: 2021;1:210008DOI: 10.52778/efsm.0008Дата: 16.08.2021

Guideline recommendations for the treatment of abdominal pain (in irritable bowel syndrome)


Abdominal pain is common and impairs quality of life. Many specialist societies across the world have formulated guidelines on the treatment of irritable bowel syndrome and all of them mention antispa ...

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Автор: Thomas Weiser, PhDEFSM: 2021;1:210010DOI: 10.52778/efsm.21.0010Дата: 16.08.2021

Treatment of acute pain: comparison of the efficacy of ibuprofen lysinate and ibuprofen


Relief that is rapid and effective is wanted when treating pain. A double-blind, placebo-controlled study investigated the efficacy, safety and tolerability of ibuprofen lysinate, ibuprofen acid and p ...

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Автор: Thomas Weiser, PhDEFSM: 2021;1:210012DOI: 10.52778/efsm.21.0012Дата: 16.08.2021

Recent meta-analysis on the efficacy of peppermint oil in irritable bowel syndrome


The meta-analysis demonstrated that peppermint oil is an effective and safe medicinal agent for treating the symptoms of irritable bowel syndrome. In seven clinical studies, peppermint oil was clearly ...

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Автор: Harald Weigmann, PhDEFSM: 2021;1:210013DOI: 10.52778/efsm.21.0013Дата: 16.08.2021

Do caffeine-containing combination analgesics cause sleepless nights?


No relevant effects on the sleep quality of subjects were found in two studies in which ibuprofen combined with 100 mg caffeine was taken three times daily. Of a total of 538 patients, medication-indu ...

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Автор: Thomas Weiser, PhDEFSM: 2021;1:210015DOI: 10.52778/efsm.21.0015Дата: 16.08.2021

Analgesics with effect enhancers – combination analgesics with caffeine


A review by the Cochrane Collaboration compared the analgesic effects of a common analgesic with a combination of the analgesic and caffeine. The addition of caffeine significantly increased the propo ...

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Автор: Thomas Weiser, PhDEFSM: 2021;1:210016DOI: 10.52778/efsm.21.0016Дата: 16.08.2021

Fall asleep quickly – wake up refreshed!


Various causes, including stress and increased media consumption, lead to a reduction or even total absence of the release of endogenous melatonin, followed by problems falling asleep. According to th ...

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Автор: Tanja Schütt, PhDEFSM: 2021;1:210017DOI: 10.52778/efsm.21.0017Дата: 16.08.2021

From virus deactivation in-vitro to clinical relevance: a glycerol and cod trypsin-containing mouth…


Trypsin combined with glycerol caused the deactivation of common cold viruses in vitro. A pilot study and a comparative multicentre study investigated the in vivo reduction in viral load and the impro ...

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Автор: Tanja Schütt, PhD и Matthias Löhn, PhDEFSM: 2021;1:210018DOI: 10.52778/efsm.21.0018Дата: 16.08.2021