Abstract: The resolution of inflammation has to date been explained by the disappearance of inflammatory messenger substances, the production of which is suppressed by non-steroidal anti-inflammatory drugs (NSAIDs). The latest studies, however, show that the resolution of inflammation is an actively controlled process, involving specialised pro-resolving mediators. Their formation is promoted by t ...
Constipation, a common ailment, often finds its first line of management at a community pharmacy. As the relevance of self-medication increases, pharmacists play a pivotal role in patient education, primary consultation, and evidence-based treatment recommendations. A crucial aspect of this role is offering relief while recognizing when to suggest additional medical consultation [1].
Headaches are most prevalent in middle age and not only have an immediate impact on the quality of life of those affected but also significantly influence their work and overall productivity. The majority of sufferers manage acute headaches through self-medication. National and international guidelines recommend acetylsalicylic acid (ASA) as a first-line treatment, with the scientific evidence for ...
Ambroxol is a mucoactive agent which has been widely used to treat acute and chronic respiratory diseases associated with a disturbance of mucus formation and transport. More recent data demonstrated that acute and chronic cough have also significant negative impact on the daily lives of adults and children. This article evaluates the impact of ambroxol on cough recovery speed and quality of life, ...
Stimulant laxatives, such as bisacodyl, sodium picosulfate (SPS), and senna, are recommended to treat constipation, based on the recent AGA/ACG guideline [1], with different levels of recommendation and evidence. They all stimulate intestinal motility, as well as water and electrolyte secretion, and accelerate intestinal transit time [2, 3]. Herbal laxatives cannot be generalized to be gentler com ...
Ambroxol increases cilia beating in the airways to remove the mucus. A new study has shed light on further details of the signalling pathway responsible for the mucokinetic action.