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Self-medication is an important pillar of healthcare

… and as with treatment prescribed by a doctor, it should be undertaken on the basis of the available evidence. Evidence for Self-Medication (EfSM) presents compact reviews of relevant studies on OTC medicines and active substances in order to enable pharmacists and other healthcare professionals to provide the best possible – and evidence-based – advice on self-medication. 

 

All EfSM articles have been peer-reviewed. They are available in German and English, and some of them in other languages ​​as well.

Acetylsalicylic acid 1,000 mg: strong evidence and good tolerability in acute headache management


Headaches are most prevalent in middle age and not only have an immediate impact on the quality of life of those affected but also significantly influence their work and overall productivity. The majority of sufferers manage acute headaches through self-medication. National and international guidelines recommend acetylsalicylic acid (ASA) as a first-line treatment, with the scientific evidence for ...

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Author: Jens SeibelEFSM: 2024;4:240051DOI: 10.52778/efsm.24.0051Date: 17.10.2024

Deciphering the daily disruption of cough: the role of ambroxol in patient recovery and quality of …


Ambroxol is a mucoactive agent which has been widely used to treat acute and chronic respiratory diseases associated with a disturbance of mucus formation and transport. More recent data demonstrated that acute and chronic cough have also significant negative impact on the daily lives of adults and children. This article evaluates the impact of ambroxol on cough recovery speed and quality of life, ...

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Author: Heidemarie Graeter, Lara Jagwanth and Anne-Laure TardyEFSM: 10.52778/efsm.24.0045DOI: 10.52778/efsm.24.0045Date: 16.10.2024

Are all stimulant laxatives the same?  A comparative perspective on bisacodyl, sodium …


Stimulant laxatives, such as bisacodyl, sodium picosulfate (SPS), and senna, are recommended to treat constipation, based on the recent AGA/ACG guideline [1], with different levels of recommendation and evidence. They all stimulate intestinal motility, as well as water and electrolyte secretion, and accelerate intestinal transit time [2, 3]. Herbal laxatives cannot be generalized to be gentler com ...

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Author: Maura Corsetti, Anna Lacerda, Ketu Patel and Alèxia AranEFSM: 2024;4:240040DOI: 10.52778/efsm.24.0040Date: 15.09.2024

The importance of real-world evidence (RWE) using the example of a diclofenac pain relief gel and a…


Real-world evidence (RWE) studies are gaining increasing importance in medical research because they investigate drug therapy use under everyday conditions. Two recent RWE studies in the field of self-medication exemplify the added value that this methodology offers for the evaluation of medicinal products.

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Author: Dr Markus ZieglmeierEFSM: 2024;4:240035DOI: 10.52778/efsm.24.0035Date: 30.07.2024

New scientific findings on the mucokinetic effect of ambroxol


The use of ambroxol is recommended by the German Society for Pneumology and Respiratory Medicine [1] to reduce symptom intensity and accelerate the recovery from acute and subacute cough. As mucoactive, it stands out by its mucokinetic effects, increasing cilia beating in the airways to remove the mucus. A new study [2] has now shed light on further details of the signalling pathway responsible fo ...

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Author: Magdalena Brodowska, Heidemarie Graeter, Paula Fontanilla and Lionel NoahEFSM: 2024;4:240037DOI: 10.52778/efsm.24.0037Date: 30.07.2024

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Featured article

New scientific findings on the mucokinetic effect of ambroxol


Ambroxol increases cilia beating in the airways to remove the mucus. A new study has shed light on further details of the signalling pathway responsible for the mucokinetic action.

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